Excimer lasers are widely used in medical technology where precise and controlled tissue interaction is required. Their ultraviolet wavelengths enable non-thermal ablation, allowing tissue to be removed with high accuracy and minimal thermal damage.
Precision Tissue Ablation with Ultraviolet Excimer Lasers
In many medical procedures, treatment outcomes depend on the ability to remove tissue with micrometer precision while maintaining full control over adjacent structures. Excimer lasers provide ultraviolet radiation that interacts directly with molecular bonds, enabling controlled, non-thermal tissue ablation. This allows reproducible surgical results across applications ranging from corneal reshaping to intravascular plaque removal, where accuracy and minimal collateral impact are essential.
MLase develops compact excimer laser sources designed for integration into advanced medical systems and minimally invasive platforms. Stable pulse energy, controlled beam characteristics, and reliable long-term operation support consistent performance in clinical environments. This enables system manufacturers to implement precise tissue ablation processes with predictable outcomes across a wide range of medical applications.
Excimer Lasers for Medical Procedures
Precise removal of biological tissue requires controlled interaction at the micron scale. Excimer lasers provide ultraviolet radiation that enables non-thermal ablation, making them ideal for delicate surgical procedures and minimally invasive treatments.
Refractive Surgery (LASIK) — Laser Vision Correction
Medical lasers are a core technology in refractive surgery, enabling highly precise reshaping of the cornea to correct refractive errors such as myopia, hyperopia, and astigmatism. In modern LASIK and PRK procedures, ArF excimer lasers operating at 193 nm remove extremely thin layers of corneal tissue with high spatial resolution and minimal thermal load
Corneal reshaping is achieved through photochemical ablation, where ultraviolet photons break molecular bonds in the tissue. This process removes corneal material with sub-micrometer precision while avoiding significant heat transfer to surrounding areas. The result is smooth ablation profiles and highly predictable tissue removal, which is essential for accurate refractive correction.
Because 193 nm radiation is strongly absorbed in corneal tissue, ArF excimer lasers have become the established industry standard for corneal ablation in ophthalmic surgery systems.
MLase GmbH develops compact medical excimer laser sources designed for integration into advanced ophthalmic platforms. High pulse stability and consistent beam characteristics support reliable performance in demanding clinical environments.
Glaucoma Treatment
Excimer lasers are used in glaucoma treatment to create microscopic drainage channels in the trabecular meshwork, improving aqueous humor outflow and reducing intraocular pressure. These procedures typically use fiber-delivered 308 nm laser pulses for highly controlled, nonthermal tissue ablation.
The treatment relies on photochemical ablation, where ultraviolet laser pulses selectively remove small portions of trabecular tissue without significant thermal effects. This enables precise laser micro drilling and micro-structuring of the drainage pathways while minimizing damage to surrounding ocular structures.
Because 308 nm excimer radiation can be efficiently delivered through optical fibers, the technology is well suited for minimally invasive glaucoma treatment systems and MIGS platforms.
MLase GmbH develops compact UV medical laser sources designed for integration into advanced ophthalmic devices. Their stable low-energy pulse operation supports reliable performance in fiber-delivered intraocular laser systems used in modern glaucoma therapies.
Laser Atherectomy
Laser atherectomy is used to remove atherosclerotic plaque inside coronary and peripheral blood vessels, restoring blood flow in obstructed arteries. The procedure uses fiber-delivered excimer laser pulses to ablate plaque and thrombus with high precision inside confined vascular lumens.
During the procedure, UV laser pulses are delivered through optical fiber-based catheter systems to the treatment site. The laser energy interacts with plaque and thrombotic material enabling controlled fragmentation and removal of the obstruction.
Because the ultraviolet energy is strongly absorbed by biological material, excimer lasers can ablate plaque while maintaining low thermal load in surrounding vascular tissue. This controlled interaction is particularly important in the narrow lumens of coronary and peripheral vessels.
Excimer-based laser atherectomy medical devices are widely used in interventional cardiology and have established a large global clinical installed base.
MLase GmbH develops medical laser sources designed for integration into catheter-based medical systems, supporting stable pulse energy and reliable long-term operation in demanding clinical environments.
Technology Advantages
Our Commitment to Quality
MLase operates as a medical device manufacturer with a quality management system certified according to ISO 13485/ EN ISO 13485. Our products are developed and manufactured to meet the highest standards of performance, reliability, and quality.
This commitment ensures that our excimer laser systems support safe and dependable operation in demanding medical applications.
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