Excimer Lasers for Medicine

Medical Applications

Excimer lasers are widely used in medical technology where precise and controlled tissue interaction is required. Their ultraviolet wavelengths enable non-thermal ablation, allowing tissue to be removed with high accuracy and minimal thermal damage.

MLase Excimer Lasers for Medicine

MLase GmbH develops compact and high-stability excimer laser sources for integration into advanced medical systems. Our solutions support precise, repeatable UV pulse delivery for clinical procedures and industrial micromachining of medical components, ensuring consistent outcomes across demanding environments.

MLase operates as a medical device manufacturer with a quality management system certified according to ISO 13485/ EN ISO 13485. Our products are developed and manufactured to meet the highest standards of performance, reliability, and quality.

Medical Laser Technology 

MLase develops compact excimer laser sources for integration into advanced medical devices such as ophthalmic surgery systems and minimally invasive treatment platforms. With stable pulse energy and high reliability, these lasers support consistent clinical performance and demanding medical applications.

Refractive Surgery (LASIK)

Medical lasers are a core technology in refractive surgery, enabling highly precise reshaping of the cornea to correct refractive errors such as myopia, hyperopia, and astigmatism. In modern LASIK and PRK procedures, ArF excimer lasers operating at 193 nm remove extremely thin layers of corneal tissue with high spatial resolution and minimal thermal load

Corneal reshaping is achieved through photochemical ablation, where ultraviolet photons break molecular bonds in the tissue. This process removes corneal material with sub-micrometer precision while avoiding significant heat transfer to surrounding areas. The result is smooth ablation profiles and highly predictable tissue removal, which is essential for accurate refractive correction.

Because 193 nm radiation is strongly absorbed in corneal tissue, ArF excimer lasers have become the established industry standard for corneal ablation in ophthalmic surgery systems.

MLase GmbH develops compact medical excimer laser sources designed for integration into advanced ophthalmic platforms. High pulse stability and consistent beam characteristics support reliable performance in demanding clinical environments.

Glaucoma Treatment

Excimer lasers are used in glaucoma treatment to create microscopic drainage channels in the trabecular meshwork, improving aqueous humor outflow and reducing intraocular pressure. These procedures typically use fiber-delivered 308 nm laser pulses for highly controlled, nonthermal tissue ablation.

The treatment relies on photochemical ablation, where ultraviolet laser pulses selectively remove small portions of trabecular tissue without significant thermal effects. This enables precise laser micro drilling and micro-structuring of the drainage pathways while minimizing damage to surrounding ocular structures.

Because 308 nm excimer radiation can be efficiently delivered through optical fibers, the technology is well suited for minimally invasive glaucoma treatment systems and MIGS platforms.

MLase GmbH develops compact UV medical laser sources designed for integration into advanced ophthalmic devices. Their stable low-energy pulse operation supports reliable performance in fiber-delivered intraocular laser systems used in modern glaucoma therapies.

Laser Atherectomy

Laser atherectomy is used to remove atherosclerotic plaque inside coronary and peripheral blood vessels, restoring blood flow in obstructed arteries. The procedure uses fiber-delivered excimer laser pulses to ablate plaque and thrombus with high precision inside confined vascular lumens.

During the procedure, UV laser pulses are delivered through optical fiber-based catheter systems to the treatment site. The laser energy interacts with plaque and thrombotic material enabling controlled fragmentation and removal of the obstruction.

Because the ultraviolet energy is strongly absorbed by biological material, excimer lasers can ablate plaque while maintaining low thermal load in surrounding vascular tissue. This controlled interaction is particularly important in the narrow lumens of coronary and peripheral vessels.

Excimer-based laser atherectomy medical devices are widely used in interventional cardiology and have established a large global clinical installed base.

MLase GmbH develops medical laser sources designed for integration into catheter-based medical systems, supporting stable pulse energy and reliable long-term operation in demanding clinical environments.

Medical Device Manufacturing

Excimer lasers enable high-precision micromachining of polymers, coatings, and thin materials used in medical devices. Their UV radiation allows clean laser ablation with minimal heat-affected zones and excellent edge quality, making them suitable for manufacturing delicate medical components.

In medical device manufacturing, excimer lasers are widely used for stripping and micro-structuring polymers and thin materials, including catheter tubing, medical polymer films, and coated components. Typical processes include the creation of micro-holes, channels, fine surface structures, and fine wire stripping.

Using ultraviolet wavelengths such as 193 nm and 248 nm, excimer lasers can ablate many polymers and thin films with high efficiency and minimal thermal effects. This enables precise feature definition and clean edges even in sensitive materials commonly used in minimally invasive medical devices.

MLase GmbH excimer laser sources are integrated into industrial micromachining platforms used by medical device manufacturing companies and system integrators, supporting reliable operation in high-precision manufacturing environments.

Anwendungsgebiete

Technology Advantages

Material-selective interaction

leverages strong UV absorption in tissues, polymers, and coatings, providing predictable ablation across multiple medical applications.

High spatial resolution

allows micrometer-scale structuring, from corneal reshaping and micro-trabecular ablation to vascular plaque removal and fine micro-features in medical devices.

Minimal thermal load

ensures surrounding structures remain intact, supporting safe, reproducible clinical and manufacturing processes.

Stable, repeatable performance

ensures reliable operation in demanding clinical environments and continuous industrial use.

ISO 13485

Our Commitment to Quality

MLase operates as a medical device manufacturer with a quality management system certified according to ISO 13485/ EN ISO 13485. Our products are developed and manufactured to meet the highest standards of performance, reliability, and quality.

This commitment ensures that our excimer laser systems support safe and dependable operation in demanding medical applications.

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